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Conclusions The discovery of ferroptosis as a distinct, iron-dependent form of regulated cell death has significantly advanced our understanding of redox biology and its relevance to cancer progression and therapy

Additionally, FSP1 is endowed with the capacity to synthesize the intermediate metabolite 6-OH-FAD, which not only functions as a crucial cofactor in enhancing the activity of FSP1 but also directly exhibits antioxidant properties by trapping free radicals

It has been reported that small gaseous molecules such as CO and NO can effectively inhibit HSP70 in tumor cells [295]