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Pro-resolving lipid mediators (Hsiao et al., 2015), PDE2 antagonists (Snell et al., 2013), antibodies directed against inflammatory cytokines (Barnes, 2018), are among the other several approaches which, at the moment, did not demonstrate a relevant clinical benefit when tested in clinical trials despite their success in animal models

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During the COVID-19 pandemic, when a flexible approach and speedy access were needed, these pathways have provided unprecedented benefits to the sponsors who were able to bring their COVID-19 indicated medicines into Australia and have them approved and reimbursed in a timely manner and to the Australian consumer

As the liver plays a crucial role in glutathione metabolism, optimizing its function can indirectly contribute to higher glutathione levels