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Life Sciences, 216 (1), 101-110

Combination regimens based on platinum compounds, taxanes and fluoropyrimidines are still standard in many disease settings and lines of therapy [1, 2]

This strategy represents a novel direction for cancer immunotherapy [233]

For instance, L-arginine is metabolized by arginase to produce L-ornithine, a precursor for both polyamines and L-prolinetwo metabolite groups intimately associated with fibrosis