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PEGylated therapeutics entered clinical development and commercialization in the 1980s

And when you feel more functional, everything else gets easier: workouts, meal prep, and even just getting through the workday

doi: 10.1038/s41392-023-01557-7

Additionally, many of the current concussion studies in pediatrics 14,15,16,17,18 use a healthy control group perhaps biasing metabolite effects towards representing general injury alterations for example due to pain, rather than concussion specifically