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Older adults also have an increased risk of alcohol use disorder due to an increase in social isolation, divorce or bereavement, and increased rates of depression, reduced alcohol metabolism, and increased alcohol toxicity that lead to an increased risk of alcohol-associated liver disease and a worse prognosis with alcohol-associated liver disease among older adults

Thus, sucrose may alter the neural circuits that encode reward and enhance the SUD drive

Conditional disruption of Raptor reveals an essential role for mTORC1 in B-cell development, survival, and metabolism

Generally, based on the structural insights into the above-mentioned fragments with MmaA4, chimeric inhibitors with improved binding affinities shall be designed