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In vitro lste NaBPC157, verabreicht in der gleichen Dosis (100 M) wie L-Arginin, in der Magenschleimhaut aus Ratten-Magengewebshomogenaten eine vergleichbare Bildung von NO aus

4 From eNOS uncoupling to hypertension: several molecular mechanisms contribute to the pathology establishment The altered NO production may be involved in the essential hypertension pathogenesis, as human studies showed that an increase in the mean diurnal BP corresponded with a reduced urinary excretion of nitrate, an index of endogenous NO generation

It was found that ALPPS surgery caused an increase in IHH secreted by activated HSCs, and activated the HH signaling pathway in hepatocytes to promote the accumulation of GLI1 in the nucleus, thereby promoting LR (Langiewicz et al., 2017

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