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The hallmarks of ferroptosis Ferroptosis is a cell death pathway that has been the focus of increasing investigation due to its theorized role in numerous human diseases

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It is important to note that oral doses may be degraded by the digestive system, compromising their effectiveness

Therefore, we aimed to identify factors affecting PK variability of busulfan in pediatric allogeneic hematopoietic cell transplantation (HCT) recipients and investigate the effect of glutathione S-transferase (GST) activity on busulfan metabolism using a semi-mechanistic population PK model