Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Pomalidomide-5'-C6-acid Synonyms CAS
Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Pomalidomide-5'-C6-acid Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by
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