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The Finkley 2005 study on 67 women aged 50 to 59 reported improvements in laxity, clarity, firmness, fine lines, wrinkles, and pigmentation across the face after 12 weeks

In another uncontrolled open-label clinical trial, fifty patients with chronic migraine were treated with an antioxidant formulation of 1,200 mg Pinus radiata bark extract and 150 mg vitamin C daily for 3 months

However, because both can stimulate the immune system, there is a theoretical possibility of an additive effect

However, it may not be suitable for individuals sensitive to cyanide or those with kidney problems, as the body must detoxify even the small amounts of cyanide