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Mitochondria have a greater contribution in the pathology of PD, oxidative stress due to excess hydrogen peroxide, hydroxy radicals, and nitrosative groups, which results in cellular death since substantia nigra is enriched with iron (Fe 2+ ) which has resulted in the toxicity to the cells 11,12

My understanding is that there's two camps on this, it seems

(2012) and Sha et al

Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease