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Antioxidant therapy acts as a double-edged sword due to the dual role of ROS as signaling molecules and damaging agents, resulting in heterogeneous treatment outcomes

Results for bacteria and fungi are shown in (a) and (b), respectively

Therefore, it is crucial to either increase the diversity of SCFA-producing microbes or specifically promote the growth and activity of SCFAs producers, especially those that generate butyrate for preventing or alleviating metabolic or immune issues stemming from estrogen dysregulation