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While dedicated large-scale trials in post-bariatric populations are ongoing, retrospective studies suggest efficacy in patients with weight regain

Copy number amplification of the Pfmdr1 gene has been shown to cause MQ resistance [22]

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Extracellular matrix promotes proliferation, migration and adhesion of airway smooth muscle cells in a rat model of chronic obstructive pulmonary disease via upregulation of the PI3K/AKT signaling pathway