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Notably, specific metabolites such as propionate exhibit protective, anti-tumorigenic functions, while others like TMAO is associated with pro-carcinogenic activities (Wang and Hu, 2025)

For example, the metabolite kynurenine has been found to play a role in the development of depression, while butyrate has been shown to improve anxiety-like behavior in animal models

10.1016/j.jnutbio.2017.07.015 187 TomonoriN.ShuM.TadashiH.KazuhiroO.MasanoriK.IchiroT.et al (2009)

The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. Obesity reviews : an official journal of the International Association for the Study of Obesity 17,10 (2016): 970-6