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13,14 Most Phase I reactions are catalyzed by the cytochrome P450 system (CYP450) (see overview of CYP450 below)

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A typical schedule is: Days 1 to 2: 75% old + 25% new Days 3 to 4: 50% old + 50% new Days 5 to 6: 75% new + 25% old Day 7 100% new diet

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