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Niederland et al., 2007) that may result in acute and long-term disruption of normal growth, but changes that occur specifically after concussions have not been examined

However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)

However, "general population" does not always account for the unique physiological state of pregnancy

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