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163 As an example, Tiriveedhi et al reported that lung transplant patients, who developed chronic lung allograft rejection, show increased defensin and decreased serum AAT levels along with high concentrations of AAT-defensin complexes in their bronchial lavage

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Additionally, decreased expression of Sequestosome 1 (SQSTM1) in diabetic keratinocytes impairs autophagy-lysosome-mediated degradation of ACSL4, and increasing ACSL4 expression could drive ferroptosis [48]

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