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& Dziadek, J

Its effects are dose-dependent: low concentrations (520 M) enhance antioxidant capacity (e.g., 20 M curcumin increased SOD activity by 47% in RAW264.7 cells) (Lin et al., 2019)

Moreover, while the drafting of this paper was underway, a 10-week, randomized, placebo-controlled, double-blind trial to evaluate the effect of NMN supplementation on metabolic function in 25 postmenopausal women with prediabetes was reported 21 , in which NMN supplementation increased muscle insulin sensitivity, insulin signaling, and remodeling in women with prediabetes who are overweight or obese 21

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