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Adverse Reactions/Side Effects In most cases, methylcobalamin is nontoxic, even in large doses

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Thus, upregulation of GPx1 was associated with poor prognosis in some but not all types of renal cell carcinoma: upregulation in kidney chromophobe cell carcinoma and renal clear cell carcinoma was an indicator of a poor prognosis, whereas in renal papillary cell carcinoma, upregulation of GPx1 was associated with better outcomes [135]