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Thus, the serine residue at position 114 of NHR-49 and potentially others within the hinge-region of NHR-49 were detected across multiple experiments which used both ectopically overexpressed and endogenously tagged forms of NHR-49

It downregulates pro-inflammatory cytokines calming chronic redness, post-treatment reactivity, and barrier-related irritation at the immune level

The LigPrep module of the Schrodinger software suite was utilized for ligand preparation

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