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Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance

Curcumin, the primary component derived from medicinal homologous foods like curcuma longa rhizome, is reported to play vital actions in organic activities, such as the numerous pharmacological functions including anti-oxidative stress, anti-inflammation and anti/pro-apoptosis in treating various diseases

Human Cu,Zn-SOD has a high degree of sequence homology (83%) with the bovine Cu,Zn-SOD, along with similarities in three-dimensional structure, domain organization, amino acid sequence, protein folding, and catalytic properties [41,42]

Glucose fluctuation increased hepatocyte apoptosis under lipotoxicity and the involvement of mitochondrial permeability transition opening