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Additionally, many of these compounds lack long-term clinical safety data in healthy, well-trained human cohorts

But its effect and safety in human body still need to be further studied

Biochim Biophys Acta 2011;1813:1938-45.ArticlePubMed 17

J Neurol Neurosurg Psychiatry 62:310318 Massicot F, Hache G, David L et al (2013) P2X7 cell death receptor activation and mitochondrial impairment in oxaliplatin-induced apoptosis and neuronal injury: cellular mechanisms and in vivo approach