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These studies also include medical pocket-sized POC devices, such as those for detecting -hydroxybutyrate (a marker of liver performance in oxidizing fatty acids) 20 and -2-microglobulin in human tear samples (an indicator of diabetes mellitus) 21

10.1083/jcb.137.4.813 141 SarrafS

DNA damage leads to inadequate DNA repair and mutations: DNA damage is typically repaired before replication, but when lesions persist or repair is faulty, as can occur via error-prone pathways like NHEJ, mutagenesis may ensue, contributing to carcinogenesis through the accumulation of alterations in key genes, as detailed in Section 3.3.1.2

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