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doi: 10.3389/fendo.2025.1592683 Received 12 March 2025 Accepted 02 June 2025 Published 24 June 2025 Volume 16 - 2025 Edited by Lynda Bourebaba, Wroclaw University of Environmental and Life Sciences, Poland Reviewed by Klaus-Dieter Schlter, University of Giessen, Germany Nawel Adjeroud, University of Bjaa, Algeria Updates Copyright 2025 Bou Matar, Zhra, Nassar, Altemyatt, Naureen, Abotouk, Elahi and Aljada

The mitophagy/autophagy system may eliminate mitochondrial ROS, thereby inhibiting the of NLRP3 inflammasome activation (Zhou et al., 2011)

National IV chain locations: Corporate chains typically offer lower vitamin C doses (1,000-5,000mg) focused on wellness rather than therapeutic applications

In experimental systems, the complex provides a controlled way to study copper-linked changes in collagen-associated pathways, inflammatory mediators, and oxidative stress markers