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[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Mentzelou M., Voulgaridou G., Papadimitriou K., Alexatou O., Deligiannidou E.-G., Serdari A., Papadopoulou S.K., Psara E., Tsourouflis G., Giaginis C

Add-back therapy with norethindrone acetate is recommended to avoid serious long-term sequelae (36)

Studies have shown that nuclear cGAS binds to nucleosomes (mainly H2A-H2B), which prevents the cGAS-DNA binding and cGAS dimerization, thereby maintaining cGAS in an inactive conformation and consequently limiting autoreactivity (3234)

These antimicrobials are also less likely to cause resistance in microbes and are suitable for long-term use, such as in food preservation