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Due to ADs complex nature, combination therapy offers greater promise than monotherapy [27]

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The Data and Monitoring Safety Board (DMSB) noted a potential difference in OS during safety review

It has been described in Causasian and Japanese populations

[61] Unlike idiopathic ASD, both males and females seem to be equally affected, indicating a diminished protective effect of gender against ASD symptoms, akin to other syndromic causes of ASD