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Higher levels of ROS can cause oxidative damage of biomolecules (e.g., proteins, nucleic acids, and lipids), dysregulation of the redox homeostasis, and subsequently cell death

Patent 4,599,232.Dura Carn is a registered trademark of Sigma-Tau Health Science, Inc

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Therefore, it may be possible that amino acid transporters and their respective amino acids exist in a continuum of feedback loops which are dysregulated within TSC tubers, but whether that is a result of dyslamination of the cortex, altered proliferation, or reduced glial-neuron communication remains unknown