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Sensitivity analyses included a mixed-effects model for repeated measures and exclusion of post-baseline data from non-adherent participants to confirm robustness

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When comparing the best peptides for weight loss directly, Retatrutide compares favorably to Semaglutide and Tirzepatide in Phase 2 weight loss magnitude, reaching roughly 24% versus 15% and 21% respectively

It exhibits resistance to enzymatic degradation in certain experimental conditions, which has made it an attractive compound for studies involving peptide stability and systemic biological activity