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Description

Hesperetin relieves cisplatin-induced acute kidney injury by mitigating oxidative stress, inflammation and apoptosis

10.1016/j.phymed.2025.157677 Phytomedicine 30 TanJ

2013;8:e81937

In particular, Nrf2 coordinates the expression of enzymes involved in the biosynthesis and recycling of glutathione (GSH), including glutamate-cysteine ligase catalytic and modifier subunits (GCLC and GCLM), glutathione synthetase (GSS), and the cystine/glutamate antiporter component SLC7A11