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What payers require for Mounjaro prior authorization For Mounjaro (diabetes indication), most payers require: Confirmed type 2 diabetes diagnosis with recent HbA1c level (typically above 7.0%) Documentation of current diabetes medications and their inadequacy (most plans require failure of metformin unless contraindicated) Step therapy documentation showing the patient has tried first-line agents before progressing to tirzepatide Prescriber specialty (some plans restrict initial prescribing to endocrinologists or require specialist consultation) The PA request uses the tirzepatide dosing schedule as part of the clinical rationale

Mar 2015;21:69-75.doi:10.1016/j.mito.2015.01.010

although this is uncommon, any history of hypersensitivity to niacinamide or NAD would be a contraindication

Nature 441, 537541