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A prominent example is their inhibition of the PI3K/Akt pathwayGA treatment in lung cancer cells led to downregulation of PI3K/Akt alongside increased p53 levels, which in turn activated downstream executioner caspases and cell cycle inhibitors (p21Cip1/p27Kip1), culminating in apoptosis and growth arrest (151)

In parallel, disruptions in hormonal homeostasis, particularly in steroidogenesis, further compromise follicular development and oocyte quality

Before starting Anthocyn-TX Tablet, inform your doctor about any existing health conditions you may have and disclose all other medications you are currently taking

However, these alterations to the microbial abundance and composition at the phylum, family and genus levels may not sufficient to adequately clarify the changes to the gut microbiota in DN patients, further investigations at the levels of species or strains are necessary in the future