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10.3109/08958379609005436 Inhal Toxicol

The gut microbiome plays an important role in healthy aging and ultimately affects host longevity (Ling et al., 2022)

After convalescent plasma transfusion, clinical conditions of the patients were found to be improved, including decreased viral loads (patients became nCOVID-19 negative within 12 days), elevated level of SARS-CoV-2-specific enzyme-linked immunosorbent assay (ELISA), neutralizing antibody titers, normalized body temperature (within 3 days in four/five patients), improved ARDS (four patients at 12 days following transfusion), successful weaning from mechanical ventilation (three participating individuals within 2 weeks of therapy), increased partial pressure of oxygen/fraction of inspired oxygen, and reduced score in sequential organ failure assessment

(See DOSAGE AND ADMINISTRATION.) Although reactions are usually evident within a few minutes, observe patients for at least one hour before administering the therapeutic dose