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1 Introduction Chronic kidney disease (CKD) represents a progressive disorder marked by ongoing kidney damage or a diminished glomerular filtration rate that persists for more than 3 months ( According to the Kidney Disease Improving Global Outcomes (KDIGO) guidelines, CKD-MBD is a systemic syndrome characterized by abnormalities in bone histology and ectopic calcification

Mehta KJ, Sharp PA

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Alpha-Arbutin: A superior brightening agent that targets hyperpigmentation and dark spots, contributing to a more uniform and radiant complexion