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Description

MEOS uses a different enzyme (Cytochrome P450 2E1 - CYP2E1) to metabolize ethanol, but still creates toxic acetaldehyde

In this way, the process of glucuronic acid conjugation dominates [13]

Front Endocrinol (2013) 4:158

As we highlighted above with recombinant mAbs, and as shown in historical dengue virus motherinfant data, the theoretical risk of ADE in CP prophylaxis is highest in the weeks following transfusion, when antibody serum neutralization titres fall to sub-protective levels