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We compared differentially expressed genes (DEGs) between DMSO-treated A375R cells (control), to cells treated with 10 M R4VPL3-1 (the full PROTAC-like molecule) or with 10 M VHL-r (the VHL binding moiety alone) for 2 h

You should consult a licensed healthcare professional before starting any health protocol and seek the advice of your physician or other medical professional if you have questions or concerns about a medical condition

To preserve your muscle mass, it is recommended, for example, not to reduce your protein intake too much

SAM levels were higher in both dwarf and wild-type mice on MET-restricted diets compared to MET-enriched diets (78% and 120%, dwarf and wild type, respectively)