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By promoting the conversion of acetyl-CoA to acetylcarnitine, carnitine reduces the ratio of acetyl-CoA/CoA, thereby reducing the activity of PDH kinase and restoring the activity of PDH, allowing more pyruvate to enter the mitochondria for oxidation to produce energy [288]

In contrast, greater MP was reached on all bouts with the 1.5 g/d dosage with gains across the five sprints of +4.9%, +1.7%, +2.7%, +2.9%, and +5.1% compared with baseline

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These approaches are often restrictive, difficult to follow over the long term and can lead to nutritional deficiencies