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In women, the pigmented patches are most often found on the labia minora

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PT-141 is a synthetic peptide that acts directly on the nervous system, activating melanocortin receptors in the brain associated with sexual desire and response

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This upregulates MITF and Tyrosinase, driving the synthesis of eumelanin (photoprotective brown pigment) over pheomelanin

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Autoradiograms were then generated by exposing the sections to Biomax MR film, and the resulting digital images were quantitatively analyzed using Image J software, with five brains analyzed per group [1]

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