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Denatonium benzoate Based on 1 publication(s) in Google Scholar Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors ( TAS2Rs ) with oral activity

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The Phase 2 trial results speak for themselves: up to 24% body weight reduction at the highest dose (12mg/week) in 48 weeks, with 25% of patients losing 30% or more of their starting weight