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163 Specifically, Dux, known for enhancing pluripotency during the transition from embryonic stem cells to 2-cell-like ESCs, induces H3K18la through a metabolic switch and p300 recruitment, boosting gene activation for pluripotency and epithelial cells and ultimately accelerating reprogramming efficiency

This was done using a numerical model: calculating a heat transfer rate for the initial body temperature due to both thermal radiation and forced convection using that heat transfer rate to calculate the amount of heat transferred over a relatively short time interval using the amount of heat transferred to calculate a resulting reduction in body temperature calculating a new body temperature by subtracting the reduction in body temperature repeat 1-5 until temperature was well beyond survival temperature, keeping track of the temperatures and times to make the graph We see that the time to mild hypothermia is actually more like 30 mins