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Free Radic Biol Med 48(11):14921500

The results of a study by Poggioli et al [64] revealed that chronic administration of DEX was associated with decreased weight gain, which was attributed to its ability to accelerate fatty acid oxidation, and decrease brown adipose tissue thermogenesis and the activity of uncoupling protein-1 mRNA[64]

Aging mouse Aged 1-year-old C57BL/6J animals were purchased from Janvier Labs (France) and quarantined in the IBS Animal Facility for 2 weeks before the experiment