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The researchers also discovered nanoparticles produce more potent and balanced serum IgG antibodies than the corresponding soluble protein mixture, and the immune responses are sustained for at least four months after the immunization

In addition, the development of intelligent microcapsule delivery systems, such as microsphere gels coated with hyaluronic acid and catechins, can protect engineered probiotics from gastric acid environments, prolong intestinal colonization time, and enhance therapeutic efficacy [422]

424,425,426 Conversely, p53 can posttranscriptionally regulate non-mtSIRT via miRNAs, while transcriptionally regulating mtSIRT through PGC1/