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A plant-based meal reduces postprandial oxidative and dicarbonyl stress in men with diabetes or obesity compared with an energy- and macronutrient-matched conventional meal in a randomized crossover study

A mechanistic study published in 2022 demonstrated that hyperoxia suppresses the SMAD3/ERK1/2 signaling pathway, leading to mitochondrial membrane depolarization, excessive fission, and fusion impairment, culminating in AT2 cells apoptosis (Jiang et al., 2022)

These findings support the potential role of targeted dietary strategies in ASD and highlight the need for larger, randomized controlled trials to clarify underlying mechanisms and long-term clinical outcomes