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Glutathione as an Antioxidant An antioxidant is broadly defined as anything that neutralizes oxidantsoften used interchangeably with free radicals

Going beyond MRI is the task of MRS

In the next step, samples were diluted with 100 mM ABC, then reduced with 5 mM TCEP (in 50 mM ABC) for 30 min at 37 C, re-alkylated with 10 mM d5-NEM, diluted with four volumes of 25 mM ABC and digested overnight with trypsin at 37 C, (shaking at 550 rpm

We and others showed that l-2-hydroxyglutarate (L2HG), a reduced metabolite of -KG by MDH1/2 or LDHA, selectively accumulated as a fundamental response to hypoxia in various primary and cancer cells (39, 72)