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The 9-week experiment comprised a 5-week demyelination period in which C57BL/6 mice were provided with 0.2% w/w CPZ added to rodent chow, followed by a 4-week remyelination period in which mice were fed CPZ-free chow

IH-1 and OH-2 cells were maintained in 10% heat-inactivated human serum (HS, Blood Bank, St Olavs University Hospital, Trondheim, Norway) in RPMI and IL-6 (2 ng/ml)