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Upon activation, STING translocates from the ER to the Golgi, where it recruits kinases such as TANK-binding kinase 1 (TBK1) and IB kinase (IKK), which phosphorylate interferon regulatory factor 3 (IRF3) and the nuclear factor-B (NF-B) inhibitor IBa, respectively

Known for its calming effects in the brain, it has been shown to support concentration and focus while it reduces irritability and low mood states

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Accordingly, the binding site residues of ATP included residues Y196, K199, R201, P235, I237, A258-G262, and G303-H305