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This route dependence is why GHK-Cu dosage cannot be expressed as a single universal figure

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Hypoxic tumor cells release vascular endothelial growth factor (VEGF), cyclooxygenase-2 (COX-2), prostaglandin E (PGE), stromal cell-derived factor 1 alpha (SDF1), and endothelial monocyte-activating polypeptide II (EMAP-II), recruiting and maintaining immunosuppressive myeloid cells

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