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doi: 10.3390/ijms23010014 119 KaY.ItoR.NozuR.TomiyamaK.UenoM.OguraT.et al

Targeted editing of tomato carotenoid isomerase reveals the role of 5 UTR region in gene expression regulation

Transcriptomic and unbiased metabolomic modeling in ndufs2 -/- larvae uncovered a host of dysregulated pathways and genes that may be downstream cellular effects of primary CI deficiency that significantly impact animal survival and health and thereby warrant investigation for potential therapeutic manipulation