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Nevertheless, most of the studies are based on animal models, and more well-designed clinical trials are required to address the potential of these ingredients when regulating intestinal barrier dysfunctions

Yin X, Jiang S, Yu J, Zhu G, Wu H, Mao C (2014) Effects of spirotetramat on the acute toxicity, oxidative stress, and lipid peroxidation in Chinese toad ( Bufo bufo gargarizans ) tadpoles

Bailey E, Field L, Rawlings C, King R, Mohareb F, Pak K-H

15 Damage-associated molecular pattern (DAMP) species released into the circulation, such as nuclear fragments and mitochondrial DNA (mtDNA), appear to recruit inflammatory cells via the innate immune system as the livers attempt to remove necrotic cell debris and promote the livers recovery phase