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Description

These tumor vessels disturb the establishment of active anti-cancer immunity at multiple steps and restrain the efficacy of ICI treatment against the tumor (Fig

P.LiangY

T cells deficient in autophagy displayed reduced SAM level, which was associated with decreased global expression of H3K27me3, increased H3K4me3 density in the promotor regions of effector genes, and enhanced anti-tumor function of mouse CD8+ T cells ( via the regulation of histone methylation