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While no direct clinical trials provide data on optimal human dosing of 6-gingerol for SLE, ginger extracts are generally regarded as safe, with human doses up to 2 grams daily (approximately 25 mg/kg for a 70 kg adult) showing good tolerability in other contexts (219)

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10.3389/fonc.2022.855019 Front Oncol

ATMs and mitochondrial iron transporters (MITs) are the two primary categories of transporters that modulate metal levels in mitochondria (Nouet et al., 2011)