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doi: 10.1016/j.chom.2014.02.005 85 MachielsKJoossensMSabinoJDe PreterVArijsIEeckhautVet al

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10.1007/s13311-019-00735-2 Neurotherapeutics

354 In addition, amitriptyline can increase the expression of Cx43 to promote gap junction intercellular communication (GJIC) between astrocytes, thereby relieving depressive symptoms